MSD

Janumet XR 50/500 mg 56 Tabs For Diabetes

14.990 KWD
1211984

Janumet XR 50 / 500 mg 56 Tablets
Janumet contain Sitagliptin + Metformin.
Sitagliptin is a dipeptidyl peptidase-4 inhibitor that increases insulin and decreases glucagon to improve glycemic control. It is therefore used in the treatment of type 2 diabetes.
Metformin belongs to the group of biguanides with anti-hyperglycemic effect. It lowers glucose in the blood and also after eating, but it does not stimulate the formation of insulin. It works by reducing the formation of glucose in the liver by blocking the breakdown of glycogen. It also increases insulin sensitivity in the muscles, which helps in Regulating blood sugar.

Points of interest:

• To reduce stomach upset, take this janumet tablets with food or just after food.

• Tell your doctor if you experience nausea, vomiting, loss of appetite or cramps.

• Metformin has slow onset of action, it may take up to 2 weeks to establish control.



Side effects of Janumet tablet:

• Malabsorption of vitamin B12.

• Nausea.

• Vomiting.

• Anorexia.

• Diarrhea.

• Headache.

• Joint pain.



Cautions:

• Metformin is excreted by kidneys, serum creatinine levels should be determined before initiating treatment and regularly thereafter.

• Decreased renal function in elderly is frequent and asymptomatic.

• As the IV administration of iodinated contrast material in radiologic studies can lead to renal failure, metformin should be discontinued prior to, or at the time of test and not be reinstituted until 48 hours afterwards.

• Contraindicated in patients with heart failure.

• Contraindicated in patients with pancreatitis.



Interactions of Janumet tablet:

• ACE inhibitors: the hypoglycemic effect of metformin is possibly enhanced when given with ACE inhibitors

• Beta-blockers: warning signs of hypoglycemia (such as tremor) with metformin may be masked when given with beta-blockers.

• Cimetidine: the excretion of metformin is reduced by cimetidine.

• Furosemide: may reduce the effectiveness of sitagliptin and other diabetic medications.

• Levothyroxine: may reduce the effectiveness of sitagliptin.



Indications:

• Janumet tablets used for Type 2 diabetes mellitus.



Size :

56 Tabs



Made In:

Take janumet tablets as per as direction of doctor.

Sitagliptin, Metformin,,,

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